Evidence Based Analysis Comprehensive Nursing Paper Example
Practice Question: In adults aged 65 years and above with venous leg ulcers, how effective is therapeutic ultrasound compared to larval therapy in the form of BioFOAM dressing for the debridement of VLU in three months?(Evidence Based Analysis Comprehensive Nursing Paper Example)
Date: 11/22/2023
| Article Number | Author and Date | Evidence Type | Sample, Sample Size, Setting | Findings That Help Answer the EBP Question | Observable Measures | Limitations | Evidence Level, Quality |
| 4 | Wiegand, C., Bittenger, K., Galiano, R. D., Driver, V. R., & Gibbons, G. W. (2017). Does non-contact low‐frequency ultrasound therapy contribute to wound healing at the molecular level? Wound Repair and Regeneration, 25(5), 871–882. https://doi.org/10.1111/wrr.12595
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Evidence: Quantitative
Type: Descriptive quantitative research. Aim: The study aimed to characterize and compare NLFU treatment intervention for VLU and standard of care on the content of fibrinogen, bacteria, and inflammatory cytokines.
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Sample:
Inclusion criteria: Adults with chronic venous leg ulcers (CVLUs) and received care in the participating clinical sites. Exclusion criteria: Not having chronic venous leg ulcers and do not receive care in the participating clinical sites. Sample size: 36 Setting: 17 clinical sites in Helsinki
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The non-contact low-frequency ultrasound (NLFU) intervention group had a higher reduction in VLU wound size (67%) compared to the standard of care (41.6%). The findings further demonstrated that NLFU. NFLU inhibits the high levels of proinflammatory cytokines and reduces the bacterial burden, improving wound healing. | Wound size
Biological markers/population in wound tissue
Wound mediator concentration, including growth factors, proteases, or cytokines. |
Small sample size
Lack of sample diversity
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Level: I
Quality: B |
Reference
Wiegand, C., Bittenger, K., Galiano, R. D., Driver, V. R., & Gibbons, G. W. (2017). Does non-contact low‐frequency ultrasound therapy contribute to wound healing at the molecular level? Wound Repair and Regeneration, 25(5), 871–882(Evidence Based Analysis Comprehensive Nursing Paper Example). https://doi.org/10.1111/wrr.12595
The permalink for the article chosen for this assignment is: (Evidence Based Analysis Comprehensive Nursing Paper Example) https://chamberlain.primo.exlibrisgroup.com/permalink/01CUCON_INST/f6kb8f/cdi_proquest_miscellaneous_1975030679
The patients receiving NLFU intervention had a higher decrease in VLU compared to those receiving SOC intervention. The study associates the significant reduction in wound size among patients receiving NLFU treatment to increase and decrease in Pro- and anti-inflammatory mediator profiles and bacteria over time. The study revealed that patients receiving NLFU treatment showed decreased fibrinogen amounts, cytokines IL-6, TNF-alpha, PF4, IL-8 amounts, TGF-beta amounts, IL-1beta concentrations in wound tissue and fluids respectively. In contrast, patients receiving SOC intervention had increased amounts of the inhibitors and decreased amounts of mediators. Equally, patients receiving NLFU intervention had reduced amounts of IL-10 concentrations.(Evidence Based Analysis Comprehensive Nursing Paper Example)
The authors proposed NLFU as a remedy to the normal standard of care. To ensure the intervention fidelity, it is crucial to characterize the wound’s age, status, and size, as these are the essential factors that hinder the short and long-term positive outcomes of intervention. Wiegand et al. (2017) argued that wound size and status/infection limits the healing process. In this case, wound size and age are biochemical markers for prolonged infection, inflammatory status, and delayed healing process of CVLUs. Characteristically, the physical therapist should encourage patients about the NLFU treatment intervention and obtain consent. Consequent to establishing rapport and obtaining consent, the therapist should combine the standard care and the NLFU intervention.(Evidence Based Analysis Comprehensive Nursing Paper Example)
Furthermore, the therapist should assess the patient’s response to treatment, including wound size and fluid content, at least once every week over the twelve-week of therapy. During the visits, it is crucial to provide education on wound health and management. According to Lindsay et al. (2017), patients’ access to wound care information and their role in wound management promotes wound self-management habits and enhances the healing process. Lastly, the therapist should observe every wound management guideline in addition to the NLFU intervention. Together, these protocols can achieve faster and more effective wound healing and management than stand-alone therapy and other standard wound therapy interventions.(Evidence Based Analysis Comprehensive Nursing Paper Example)
References
Wiegand, C., Bittenger, K., Galiano, R. D., Driver, V. R., & Gibbons, G. W. (2017). Does non-contact low‐frequency ultrasound therapy contribute to wound healing at the molecular level? Wound Repair and Regeneration, 25(5), 871–882.(Evidence Based Analysis Comprehensive Nursing Paper Example) https://doi.org/10.1111/wrr.12595
Lindsay, E., Renyi, R., Wilkie, P., Valle, F., White, W., Maida, V., … & Foster, D. (2017). Patient-centered care: a call to action for wound management. Journal of wound care, 26(11), 662-677.(Evidence Based Analysis Comprehensive Nursing Paper Example) https://doi.org/10.12968/jowc.2017.26.11.662
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